Friday, August 26, 2005

Celebrating my first paper as a first author

The third issue of PLoS Computational Biology is out and in it is the first paper I publish as a first author. It took some time to get it published but I am grateful for the useful reviewer comments. The two main points about this work is that SH3 domains preferentially bind unstructured protein regions and that there is an "optimal" divergence time that one should consider when selecting species to use when looking for conservation of SH3 target sites. If you are interested in this last point I encourage you to read the excellent paper by Sean R. Eddy "A Model of the Statistical Power of Comparative Genome Sequence Analysis" in PLoS Biology.