The first issue of PLoS Computational Biology is out. The journal's editors want this to be one of the main forums for the people working in the field of computational biology but so far what I would say is that it is nice to have another open access journal where we can aspire to publish our work.
I would like to point out the interesting perspective by Sean R. Eddy. Among several other interesting points he argues for interdisciplinary people instead of interdisciplinary teams and how the recent "big science" mentality might actually hinder innovation.